BLOOD-BRAIN BARRIER TO PERTECHNETATE FOLLOWING DRUG-INDUCED HYPOTENSION
نویسندگان
چکیده
منابع مشابه
P45: The Role of Blood-Brain Barrier Breakdown Following Traumatic Brain in Post-Traumatic Epilepsy
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملEvolving Drug Delivery Strategies to Overcome the Blood Brain Barrier
The blood-brain barrier (BBB) poses a unique challenge for drug delivery to the central nervous system (CNS). The BBB consists of a continuous layer of specialized endothelial cells linked together by tight junctions, pericytes, nonfenestrated basal lamina, and astrocytic foot processes. This complex barrier controls and limits the systemic delivery of therapeutics to the CNS. Several innovativ...
متن کاملBrain Mini-Workshop: Blood Brain Barrier and Targeted Drug Delivery
Drugs are currently being developed for the treatment of serious brain disorders including glioblastoma, Parkinson’s disease, and Alzheimer’s disease. These include chemotherapeutic drugs and those based on neurotrophic factors such as glial cell-derived neurotrophic factor (GDNF), brain-derived neurotrophic factor (BDNF), and neurturin (NTN). Neurotrophic factors have therapeutic potential for...
متن کاملPharmacodynamic Analysis of Magnetic Resonance Imaging-Monitored Focused Ultrasound-Induced Blood-Brain Barrier Opening for Drug Delivery to Brain Tumors
Microbubble-enhanced focused ultrasound (FUS) can enhance the delivery of therapeutic agents into the brain for brain tumor treatment. The purpose of this study was to investigate the influence of brain tumor conditions on the distribution and dynamics of small molecule leakage into targeted regions of the brain after FUS-BBB opening. A total of 34 animals were used, and the process was monitor...
متن کاملCerebral complications following induced hypotension.
Over an 8-year period (1977-1984), 1,802 otorhinolaryngological procedures were performed under controlled hypotension. Four patients showed symptoms of cerebral damage post-operatively. One patient had pre-operative unrecognized stenosis of the internal carotid artery, another a hypoplastic vertebral artery. In this female patient, the head had been strongly rotated to the side to expose the s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1989
ISSN: 0007-0912
DOI: 10.1093/bja/62.4.402